Blog Posts - Parkinson's Disease



Effects of titanium dioxide nanoparticles on α-synuclein aggregation and the ubiquitin-proteasome system in dopaminergic neurons. - PubMed - NCBI

Dopaminergic neurons (PC12 cells) were treated with different doses of titanium dioxide nanoparticles (TiO2-NPs), to investigate their effects on α-Synuclein (α-Syn) aggregation and their mechanism of action. Western blotting and immunofluorescent...
by PolygenicBlog on Dec 20, 2016

Parkinson's Disease Linked to Microbiome | Caltech

Caltech scientists have discovered for the first time a functional link between bacteria in the intestines and Parkinson's disease (PD). The researchers show that changes in the composition of gut bacterial populations—or possibly gut bacteria them...
by PolygenicBlog on Dec 3, 2016

Appeal to stop deportation of 77 year old Parkinson's disease sufferer

Appeal from M. Nadeem to support his petition LINKMy father, Hakeen Muhammad Haleem, is a frail ailing 77 year old. He has been staying with me and my family, at our expense, since 2010. He is a widower with a number of serious health issues who n...
by wembleymatters on Aug 30, 2016

Parkinson's Disease Diagnosed by Salivary Gland Biopsy

Taken from WikipediaDiagnosing Parkinson's Disease (a degenerative neurological disorder) is hard, usually a clinical exam and assessment of symptoms by a neurologist with at best about an 80% accuracy rate. There is no "test" per se that c...
by Fauquier ENT on May 2, 2016

Parkinson’s Awareness Week

With any luck, fragments of bone will be shattered away and lodge themselves in the Know It All’s brain too. Continue reading →...
by Sitting Comfortably? on Apr 19, 2016

Groundwater pesticide levels and the association with Parkinson disease. - PubMed - NCBI

It is unclear whether exposure to environmentally relevant levels of pesticides in groundwater is associated with an increased risk of Parkinson disease (PD). The purpose of this study was to examine the relationship between PD and pesticide levels i...
by PolygenicBlog on Mar 3, 2016

Alpha-synuclein expression restricts RNA viral infections in the brain. - PubMed - NCBI

We have discovered that native, neuronal expression of alpha-synuclein (Asyn) inhibits viral infection, injury, and disease in the central nervous system. Enveloped RNA viruses such as West Nile virus (WNV) invade the central nervous system (CNS) and...
by PolygenicBlog on Jan 2, 2016

Hepatitis C virus infection as a risk factor for Parkinson disease: A nationwide cohort study.

OBJECTIVE: To determine whether hepatitis C virus (HCV) infection is a risk factor for developing Parkinson disease (PD). METHODS: This nationwide population-based cohort study was based on data obtained from a dataset of the Taiwan National Health I...
by PolygenicBlog on Dec 26, 2015

Pesticide found in milk decades ago may be associated with signs of Parkinson's

For the study, 449 Japanese-American men with an average age of 54 who participated in the Honolulu-Asia Aging Study were followed for more than 30 years and until death, after which autopsies were performed. Tests looked at whether participants had...
by PolygenicBlog on Dec 10, 2015

Inflammation linked to weakened reward circuits in depression

About one third of people with depression have high levels of inflammation markers in their blood. New research indicates that persistent inflammation affects the brain in ways that are connected with stubborn symptoms of depression, such as anhedoni...
by PsyPost on Nov 20, 2015

‘Stop neurons’ in the brainstem make us halt when we walk

A population of ‘stop cells’ in the brainstem is essential for the ability of mice to stop their locomotion, according to a new study by scientists at Karolinska Institutet in Sweden. In an article published in the journal Cell, they repo...
by PsyPost on Nov 20, 2015

Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neurones

"Exposure to environmental chemicals has been implicated as a possible risk factor for the development of neurodegenerative diseases. Our previous study showed that methylmercury (MeHg) exposure can disrupt synthesis, uptake and metabolism of dopamin...
by PolygenicBlog on Nov 13, 2015

Parkinson's Disease and Pesticides Exposure: New Findings From a Comprehensive Study in Nebraska, USA. - PubMed - NCBI

"The association between exposure to agricultural pesticides and Parkinson's Disease (PD) has long been a topic of study in the field of environmental health. This research takes advantage of the unique Nebraska PD registry and state-level crop class...
by PolygenicBlog on Nov 5, 2015

Cancer drug shows promise for reversing symptoms of Parkinson’s disease, small U.S. study shows | CTV News

A small but encouraging study appears to show that a drug already available on the Canadian market has the potential to reverse symptoms of Parkinson’s disease, lending new hope to researchers looking for cures to neurodegenerative diseases. The U...
by PolygenicBlog on Oct 19, 2015

Dr. James R. Eells Discusses New Neurotransmitter Therapy Research

FOR IMMEDIATE RELEASE Free Press Release Submitted by dreells.com         Press Release Distribution Dr. James R. Eells offers a wide range of specialized medical treatments that are personalized for his patients’ needs...
by Free PR Online on Jul 23, 2015

Occupational exposures and Parkinson's disease mortality in a prospective Dutch cohort. - PubMed - NCBI

We investigated the association between six occupational exposures (ie, pesticides, solvents, metals, diesel motor emissions (DME), extremely low frequency magnetic fields (ELF-MF) and electric shocks) and Parkinson's disease (PD) mortality in a larg...
by PolygenicBlog on Jul 18, 2015

Colonic bacterial composition in Parkinson's disease. - PubMed - NCBI

INTRODUCTION: We showed that Parkinson's disease (PD) patients have alpha-synuclein (α-Syn) aggregation in their colon with evidence of colonic inflammation. If PD patients have altered colonic microbiota, dysbiosis might be the mechanism of neuroi...
by PolygenicBlog on Jul 17, 2015

Parkinson's disease may begin in the gut

New research indicates that Parkinson's disease may begin in the gastrointestinal tract and spread through the vagus nerve to the brain. We have conducted a registry study of almost 15,000 patients who have had the vagus nerve in their stomach sever...
by PolygenicBlog on Jun 24, 2015

St. Jude Medical (STJ) FDA OKs Brain Implant for Parkinson’s Symptoms; Charles Schwab (SCHW) PT Boosted

 St. Jude Medical Inc. (STJ) The U.S. Food and Drug Administration (FDA) has approved STJ‘s Brio Neurostimulation System, an implantable deep brain stimulation device to help reduce the symptoms of Parkinson’s disease and essential tremo...
by CRWE-PR Finance on Jun 13, 2015

FDA Approves Brain Implant to Help Reduce Parkinson’s Disease and Essential Tremor Symptoms

Las Vegas, NV / CRWEPRESSRELEASE / June 12, 2015 / The U.S. Food and Drug Administration today approved the Brio Neurostimulation System, an implantable deep brain stimulation device to help reduce the symptoms of Parkinson’s disease and essential...
by CRWE-PR Finance on Jun 12, 2015


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