Blog Posts - Pyrogens



Non-endotoxin Microbial Pyrogens

Pyrogens of microbial origin need to be considered in relation to the risks they pose to pharmaceutical products. Despite the low theoretical risk posed by non-endotoxin pyrogens, questions of their occurrence and risks are sometimes raised by regula...
by Pharmaceutical Microbiology on Jun 22, 2015

Understanding Fever Better

Fever (rise in body temperature above normal range of 36.5–37.5 °C or 98–100 °F) occurs due to increase in temperature set-point in hypothalamus, triggered by pyrogens. Pyrogens are chemicals that raises body temperature and released due to in...
by Health Blog on Jan 13, 2014

Pathogenesis of Fever

Exogenous pyrogens (infections, toxins, etc.) are produced In response, immune system cells release endogenous pyrogenic cytokines into circulation Immune system cells: monocytes, macrophages, endothelial cells, B-lymphocytes, mesangial cells, kerati...
by Intense Cogitation on Oct 21, 2013

Pathogenesis of Fever

Exogenous pyrogens (infections, toxins, etc.) are produced In response, immune system cells release endogenous pyrogenic cytokines into circulation Immune system cells: monocytes, macrophages, endothelial cells, B-lymphocytes, mesangial cells, kerati...
by Intense Cogitation on Oct 21, 2013


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